The study was conducted to investigate the effect of family socio-economic status on sexual behaviour among adolescent girls in Fiapre Community in the Sunyani West District. The study focuses on, the extent of sexual activities among female adolescents and influence of parental education on female adolescent sexual behaviour. The study employed a survey design to achieve the objectives of the study. Stratified and simple random was used with a sample size of 100 respondents. Structured questionnaire comprising of open and close-ended questions was designed for the study. The Statistical Package for Social Sciences (SPSS) version 20 and Microsoft Excel (2010) were used to process the data. The study found that the level of sexual activities among female adolescent girls age 13-19 years in Fiapre community was high (64%). The study revealed that out of 120 adolescents’ girls contacted, 77 of them ever had sexual intercourse. The study revealed that the educational level of the father had a weak (p = 0.042) association with female adolescent engagement in sexual intercourse whereas the association between maternal education and female adolescent engagement in sexual intercourse was insignificant (p = 0.186). The study found that mothers’ employment status has strong association with adolescents who have engaged in sex before (p = 0.001). Fathers’ employment status was also significantly associated with engagement of sexual intercourse by female adolescents (p<0.018) in Fiapre. It was found that, the monthly income of the father had a significant (p = 0.029) association on adolescents who have engaged in sexual intercourse before. Also, mothers’ monthly income also has significantly (p = 0.002) associated with adolescent engagement in sexual intercourse. The study further found that only mother’s monthly income had a significant (p = 0.001). Relationship with the number of sexual partners of the female adolescents. The monthly income of fathers was insignificantly (p = 0.276). Associated with the number of sexual partners of adolescents. The study therefore recommends that the Ghana Education Service (GES) should incorporate sex education into the educational system at the basic level as a course in order to enlighten young adolescents’ dangers of early sex and its consequences. The study also recommends that educated parents should educate their children and also encourage them to attend adolescent corners in the various health centres within the community for counselling regarding their sex life.